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How can we revolutionize medical imaging while safeguarding sensitive patient data? We believe the answer is federated learning, an AI approach that enables collaborative innovation without compromising privacy. In this post, we delve into the work of Adway Kanhere, Research Engineer at the University of Maryland School of Medicine, and his team, who are pioneering privacy-preserving AI solutions in healthcare as part of the Flower Pilot Program.
Transforming Medical Imaging with Federated Learning
Medical imaging is critical in modern healthcare, but it presents significant challenges for federated learning: data heterogeneity across institutions, resource-intensive manual annotations, and privacy concerns. Traditional FL methods often fall short, especially for complex tasks like 3D image segmentation. Our team tackled these hurdles by developing secure, distributed AI systems that empower institutions to collaborate while retaining control over their data.
Our work addresses some key challenges in federated learning for medical imaging:
- Data Heterogeneity: Variations in imaging protocols, scanner settings, and acquisition parameters lead to inconsistent datasets across institutions. This variability makes it difficult to build generalizable FL models.
- Resource-Intensive Annotations: Radiologist’s manual labeling is time-consuming and often limited to specific anatomical regions, resulting in partially labeled datasets where each site is focused on a particular organ of interest within the same field of view.
To solve these issues, our team developed the Human Anatomical Mapping Project, which leverages federated learning to harmonize collaboration across institutions while accommodating unique data protocols and partial annotations.

Transformative Collaboration: Flower and MONAI
Our partnership with the Flower team was more than a collaboration—it was a catalyst for innovation. By leveraging Flower’s FL framework, we integrated it with the MONAI 3D U-Net models to create a powerful platform for distributed medical image analysis. Each institution maintained its unique preprocessing pipelines while contributing to a shared knowledge base, setting the stage for true collaboration.
Through regular discussions with the Flower team, we engaged in an iterative process of development, testing, and refinement. This collaboration involved significant technical challenges: adapting our codebase to integrate with Flower’s architecture, implementing custom aggregation strategies for medical imaging, optimizing state-of-the-art federated learning approaches, and developing a robust deployment framework accessible to researchers. This journey has deepened our understanding of both the technical complexities and broader implications of building privacy-preserving collaborative systems for real-world medical applications.
A Milestone Moment: CVPR 2024 Demo
A significant milestone in our journey was the opportunity to present a demo of our work at the Data Curation and Augmentation in Medical Imaging (DCAMI) workshop at CVPR 2024. This platform allowed us to demonstrate the practical implementation of our research through a live federated learning deployment. We established a globally accessible federation where researchers worldwide could contribute to training 3D segmentation models using our developed codebase and the Medical Segmentation Decathlon challenge datasets. As we reflect on our progress, our work within the Flower Pilot program has helped us in expanding our group’s efforts in FL applications for medical imaging. We anticipate scaling our framework to accommodate diverse imaging tasks and protocols, with integration to use more medical imaging frameworks and datasets, and focusing on challenges such as adding/dropping clients while preserving global model performance.
Advancing Research Through the Flower Pilot Program
The evolution of artificial intelligence increasingly points toward federated architectures, particularly in privacy-sensitive domains like healthcare and finance. Through initiatives like the Flower Pilot Program, researchers can actively participate in developing these crucial technologies. For researchers considering future program cohorts, the initiative provides valuable opportunities for technical development and collaborative innovation. The program’s framework supports both independent investigation and guided development, providing conditions conducive to addressing complex research challenges. We encourage interested researchers to consider how their work might benefit from and contribute to this evolving ecosystem of federated learning innovation and consider applying to the next batch of the Flower Pilot Program.
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